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Home » Losing Fat While Gaining Muscle With Protein

Losing Fat While Gaining Muscle With Protein

Today's DietitianToday's Dietitian3 Mins ReadSeptember 18, 2025
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Researchers at McMaster University in Hamilton, Ontario, Canada have uncovered significant new evidence in the quest for the elusive goal of gaining muscle and losing fat, an oft-debated problem for those trying to manage their weight, control their calories, and balance their protein consumption.

Scientists have found that it’s possible to achieve both, and quickly, but it isn’t easy.

For the study, 40 young men underwent a month of hard exercise while cutting dietary energy by 40% of what they’d normally require.

“It was a grueling affair,” says Stuart Phillips, PhD, a professor in the department of kinesiology at McMaster and senior investigator on the study. “These guys were in rough shape, but that was part of the plan. We wanted to see how quickly we could get them into shape and have them lose some fat, but still retain their muscle and improve their strength and fitness,” he says.

The researchers divided their subjects into two groups. Both groups went on a low-calorie diet, one with higher levels of protein than the other. The higher-protein group experienced muscle gains—about 2.5 lbs—despite consuming insufficient energy, while the lower-protein group didn’t add muscle.

The lower-protein group at least had the consolation of not losing muscle, which is a predictable outcome of cutting calories and not working out, researchers say.

“Exercise, particularly lifting weights, provides a signal for muscle to be retained even when you’re in a big calorie deficit,” Phillips says.

Researchers were intrigued because the high-protein group also lost more body fat.

“We expected the muscle retention,” Phillips says, “but were a little surprised by the amount of additional fat loss in the higher protein consuming group.”

The results showed that the high-protein group lost about 10.5 lbs, and the low-protein group lost only 8 lbs. All of the participants, by virtue of the demanding six-days-a-week exercise routines, got stronger, fitter, and generally in much better shape.

However, researchers caution this regimen isn’t for everyone.

“We designed this program for overweight young men, although I’m sure it would work for young women too, to get fitter, stronger, and to lose weight fast. It’s a tough program and not something that’s sustainable or for those looking for quick and easy fix,” Phillips says. “We controlled their diets, we supervised the exercise, and we really kept these guys under our ‘scientific’ thumb for the four weeks the participants were in the study.”Phillips and his team hope to conduct a follow-up study on women and also explore a different approach that he says will be “a little easier and much more sustainable.”

— Source: McMaster University

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