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Editor's E-Note
Puzzling Through PCOS*
*On May 12, 2026, PCOS was renamed polyendocrine metabolic ovarian syndrome (PMOS) by an international agreement of more than 50 patient and professional organizations to better reflect the scope of the condition.
Polycystic ovary syndrome (PCOS) is a challenging and complex condition affecting 10% to 13% of women worldwide, according to the World Health Organization. As research advances, more distinct subtypes emerge that may guide precision medicine, including nutrition, interventions. In this month’s E-News Exclusive, we share findings from a recent study on PCOS subtypes as well as discuss considerations for nutrition support.
After reading the article, visit TD’s website at www.TodaysDietitian.com to read the digital edition of our May/June issue, featuring our cover story bringing further attention to National Women’s Health Month in May, “The Role of Nutrition in Endometriosis.” You’ll also find features on how emulsifiers might influence multiple aspects of gut health, ways to promote agricultural resilience, and interdisciplinary insights for RDs in light of the new government requirements for including more nutrition in medical education.
Please enjoy the E-Newsletter and give us your feedback at TDeditor@gvpub.com, and don’t forget to like us on Facebook and follow us on X, formerly known as Twitter.
— Heather Davis, MS, RDN, LDN, editor |
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Polycystic Ovary Syndrome* Subtypes and Precision Medicine
By Heather Davis, MS, RDN, LDN
*On May 12, 2026, PCOS was renamed polyendocrine metabolic ovarian syndrome (PMOS) by an international agreement of more than 50 patient and professional organizations to better reflect the scope of the condition.
Once upon a time, polycystic ovary syndrome (PCOS)—a reproductive and metabolic multisystemic condition with impacts across the lifespan—was a broad diagnostic term capturing a group of women, not all of whom fit neatly into a single category. As research and clinical understanding advances, we now know there are meaningful ways to subdivide the diagnosis and that this greater specificity can impact intervention selection and success. Unsurprisingly, lifestyle interventions including nutrition support are considered some of the most important and effective, but improved understanding of subtypes may help guide those treatment approaches more precisely.
PCOS affects roughly 11% to 13% of women worldwide.1 Although PCOS famously can negatively impact fertility, its consequences don’t stop there, revealing a complex pathophysiology that touches multiple systems and can introduce different metabolic dysregulations throughout the body. The most common symptoms of PCOS include menstrual dysfunction, infertility, hirsutism, acne, and obesity.2 However, so-called “lean type” PCOS is increasingly recognized and these patients often present with a favorable metabolic profile. By contrast, obese PCOS patients typically have higher blood pressure, blood lipid, and blood glucose levels. Importantly, insulin resistance is a key feature of PCOS, and obesity has been implicated in the pathogenesis of this condition.3 Even so, studies also indicate that when compared with the general population, lean PCOS patients are at a higher risk of developing metabolic disorders. Even if their body weight is within the normal range, they may have underlying metabolic problems such as mild insulin resistance or abnormal lipid metabolism.3
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The Role of Real-World Food Testing in Celiac Disease Management
NIMA Partners, Inc, maker of the portable NIMA Gluten Sensor, announces the formation of its Clinical Advisory Board—a group of leading clinicians and dietitians tasked with exploring how emerging food-testing technologies may fit into the future of celiac disease management.
Celiac disease affects an estimated 3.4 million Americans and currently has no treatment beyond strict gluten avoidance. But adherence remains difficult due to hidden gluten, inconsistent labeling, and cross-contamination risks in everyday settings like restaurants, travel, and social gatherings. These challenges can lead to both physical symptoms and ongoing anxiety for patients and families.
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How Eating Primes Immune Cells for Future Responses
Diets and healthy eating habits hold promise for preventing and treating diseases, but far less is known about acute effects on the immune system shortly after a meal.
In a study published recently in Nature, a University of Pittsburgh team found that eating creates a temporary metabolic state that influences the function of T cells—immune cells that help the body detect and fight infection and disease, including cancer. In experiments in mice and humans, T cells collected after a meal showed a metabolic and functional advantage over those collected after fasting. The findings suggest that eating can have a lasting effect on how immune cells respond when they are activated—a factor that could be relevant for T cell-based immunotherapies, such as CAR T cell therapy, as well as for responses to infection.
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CPE Monthly
In the May/June issue of Today’s Dietitian, take an in-depth dive into GLP-1 receptor agonists and injectables used for weight management. Read the CPE Monthly article, take the 10-question online test at CE.TodaysDietitian.com/CPEmonthly, and earn two CPEUs!
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Read Your Body
Read Your Body is a versatile data recording tool suitable for menstrual cycle tracking, including fertility awareness-based methods. The app offers no auto-interpretations or predictions and functions as a highly customizable digital chart. Record personal insights to understand your unique patterns and support your wellbeing. Monitor the effects of lifestyle factors like exercise, nutrition, self-care, stress levels, and sleep. By default, all charting data is stored only on your phone for maximum privacy, and you can export or delete your charting data at any time inside the app. Learn more » |
In the July/August Issue
• Reframing Weight Maintenance After Weight Loss Medications
• Family-Based Treatment in Pediatric Eating Disorder Care
• Culinary Sports Nutrition
• The Athlete Paradox |
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COVER STORY
The Role of Nutrition in Endometriosis
Certain dietary patterns may reduce symptom severity by reducing inflammation and modulating hormone levels. RDs with expertise share clinical wisdom for patients diagnosed with this challenging condition.
FEATURE
Interdisciplinary Care Starts Here
Dietitians can complement medical resident training through educating up-and-coming providers about the clinical necessity of nutrition therapy, modeling collaborative care, and reinforcing the value of referrals to nutrition experts.
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